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Most experts define infertility as a condition of not being able to conceive after at least one year of trying. It is also called sterility.


There are several different approaches to treating infertility; besides the treatment of the underlying condition, two most attractive and effective treatment forms are medications and ART (assisted reproductive technology).

Medications

Some of the most commonly used medications are:

Clomiphene citrate (Clomid®)
An oral medicine used to treat infertility by inducing ovulationacting on the pituitary gland. It is often used in women who have PCOS, a condition that interferes with normal ovulation. 

Human menopausal gonadotropin or hMG
Most commonly used medications from this group are Repronex and Pergonal. Unlike the previous group, these medications act directly on the ovaries to stimulate ovulation, and are usually administrated via injection. Another group of medications works the same way – the Follicle-stimulating hormones.

Gonadotropin-releasing hormone (Gn-RH) analog
These medications also work on the pituitary gland to cause ovulation, often administered in the the form of a nasal spray.

Metformin (Glucophage®)
This drug is widely used by women who have insulin resistance or Polycystic Ovarian Syndrome (PCOS). It helps lower the level of male hormones in women with these conditions, which normally induces ovulation.

Bromocriptine (Parlodel®)
Sometimes ovulation is blocked because of high levels of Prolactin, a hormone which normally induces milk production, but can block ovulation when present in excessive amounts.
 

Assisted reproductive technology

ART is an extremely effective method that has revolutionized the treatment of infertility.

The most common forms of ART include:

In vitro fertilization
This method involves fertilization done outside of the body. The main indications for this method are blockade of fallopian tubes or a low sperm count. First, women are injected with a medication that causes them to produce lots of eggs, which are later removed from the woman. In the lab, they are mixed with spermatozoids, and after fertilization, implanted into the woman's uterus again.

Zygote Intra-fallopian transfer (ZIFT)
This is a similar method with only one difference - fertilization does occur in the laboratory, but the young embryo is transferred to a fallopian tube instead of the uterus.

Gamete intrafallopian transfer (GIFT)
Using this method, fertilization occurs in the woman's body instead of a lab.

Intracytoplasmic sperm injection (ICSI)
A single sperm is injected directly into a mature egg. This method is used only in cases of serious conceptive problems.
 

Prevention of infertility

Unfortunately, in a vast majority of cases, infertility isn't preventable. However, simple avoidance of drugs, tobacco, and alcohol consumption may contribute to a higher sperm count. A high atmosphere or water temperature can also lower the sperm count by affecting sperm production and motility, which is why it’s recommended to avoid hot tubs and steam baths.

A woman, on the other hand, can directly affect her ability to become pregnant.

Some of the most common methods are:

  • Regular exercises could be the key because research has shown that it can help in maintaining a normal ovulatory cycle. Of course, exercising intensively can make woman’s periods irregular or even absent.
  • Obesity can modify certain hormones in your body and make pregnancy difficult.
  • As previously mentioned, alcohol, tobacco, and drugs should be avoided. Also try to limit your daily intake of caffeine to no more than 250 milligrams per day.

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