I suffer with M.E. However my mouth errupts with painful black mouth blisters, they will pop up for no apparent reason, they are not food related, around the time they appear, i am quite unwell, last year I was hospitalized with a blister that became the size of a golf ball at the back of my throat, it was cutting my air ways off, it did burst and sealed itself off and filled with blood again and had its own blood supply for a while, it kept me in hospital for a few days, NOBODY had seen anything like it!. however, it left me ill for some considerable time. Could this be M.E. related, or is it something else? I would be grateful if you could help, because no one else can, yours greatfully, pam puhlhofer.