i have been taking duromine for 2 weeks now. the first few days was hell! but stick with it people, it is worth it! i have lost 4kg in 2 weeks. had a few side effects during the 1st week, but hardly anything now. everyone is different, what works for 1 person, may not work for another, you all know your own bodies, if it is not working for you.. STOP! ask you doctor for a lower dose, or discontinue completely. i think the best advice i can give you is, use duromine for a kickstart, don't eat junky foods, (sigh, i know!) and exercise when ever you can. good luck guys! :-)