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Hello there norine,
Unfortunately there is not much you can do to help your sister in this situation. It is necessary for her to visit her doctor and to get new medications if the old ones aren’t working properly and judging the pain she has been experiencing because of the bad circulation it is very likely that her body got adjusted to the anti-inflammatory medications she has been taking so far.
Also, it is very common situation that medications aren’t helping with the pain. My aunt, she is suffering from the Raynaud’s as well, has managed to deal with this pain by working out. This is also good way to improve the blood flow. Keep us posted about your sister’s condition and I hope that everything will turn out just fine.
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