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"If you have unprotected sex with a man that takes prescription pain killer (methadone) that comes in me will it show up on your drug test. we are married"

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Drugs can be found in the bloodstream via a blood test, sperm can not. So your answer is no.
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even iftedrugs could be transfered this way Metadone doesn't show up on most drug tests. it is not the same as an opiate. thy can test for it but te likely hood of a standard drug test for work having it i low and even then having sex wth him will not make you possitive for that.
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