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Have you talked with your DR about checking your thyroid levels or anti thyroid antibodies could help narrow it down
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Within 8 days of using a progesterone cream (the kind made from yams) I have been hive free for over 2 years. My hives were debilitating and eventually led to face and tongue swelling, loss of voice...fortunately about the time they became more severe, I discovered the cause and the progesterone cream. Good Luck!
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to begin with, prednisone is NOT the most suitable treatment. you have to use antihistamines (i.e. loratadina twice a day) as requiered. if the hives appear regardeless of the menses, they could be caused by food allergy otherwise, treatment with antihistamines previous to the menses is safe, adecuate y can be used as long as you need.
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I have now had this for over a year last October. I have seen every doctor possible. No cure but the best way for me not to experience the hives has been a combination of Methotrexate with Spironolactone. Have tried everything and this is all that has worked other than massive doses of Prednisone which you can't stay on. My docs say to pray for spontaneous remission. 50% cure within one year, 70% within 2 and 90% within 3 - the other 10% don't heal. Praying I am not in the last 10%.
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