I'm female,48. Losing so much hair in the temple region, that I actually have bald spots there. Is this a symptom of disease??
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Yes, but it's a very minor symptom for a few diseases. It's also common in healthy people. There's a minoxidil formulation for women you may want to try after discussing with your doctor, though my view is it's not worth using (the hair looks a little different, and the solvent irritates the scalp of many people).
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