metformin hcl 500 mg, a medication commonly prescribed for type 2 diabetes, can lead to weight loss in some individuals. This effect is not fully understood, but several factors contribute. Metformin helps improve insulin sensitivity, which reduces insulin levels in the body—a hormone that promotes fat storage. It also lowers appetite in some users, leading to reduced calorie intake. Additionally, Metformin may affect how the gut absorbs and processes glucose and fat, indirectly supporting weight loss. Some people also experience mild gastrointestinal side effects like nausea or diarrhea, which can contribute to reduced food intake, especially early in treatment. While not a weight-loss drug, Metformin often results in modest but steady weight reduction, particularly in people who are overweight or have insulin resistance. However, its effectiveness for weight loss varies and is best supported with a healthy diet and regular exercise.

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