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Little formal research has been conducted on the topic of interactions between the drug LSD and antidepressants. BUT... if you look around the internet, you will find that it is not at all difficult to find LSD users who are also on antidepressants who report some very bad interactions. Lithium and tricyclic antidepressants are supposedly a bad combination (as in can cause death and seizures, that kind of bad) with LSD, and SSRIs reduce the effect LSD has on you.
This is definitely something to keep in mind before you use LSD again. What antidepressants are you on, if I may ask?
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one of my friends was off his anti-depressants and had a horrible trip, if he was taking his anti-depressants then he would have had a better trip, hence the anti depressant would take his mind off what he was thinking about.
but he was also crashing off 4 tablets of ecstasy.
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