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What is divalproex?

Divalproex is an anticonvulsant medication that is used to manage certain types of epilepsy, migraine disorders, and bipolar mood disorder which is a mental health condition associated with alternating phases of mania and depression.

Side effects associated with this medication include:

  • Confusion
  • Emotional lability leading to uncontrolled and spontaneous crying
  • Delusions (having a false sense of beliefs)
  • Euphoria (feeling "high")
  • Headaches
  • Nausea
  • Vomiting
  • Nervousness
  • Loss of appetite
  • Paranoia
  • Rapid weight gain or unusual weight loss
  • Trouble with sleeping
  • Tingling sensation in the hands or feet
Signs of Divalproex overdose include fainting, changes in one's level of consciousness, a slow or irregular heartbeat, or going into a coma. If any of these issues are noticed or experienced then immediate medical attention should be sought.


Marijuana contains the chemical compound known as tetrahydrocannabinol (THC) which causes a sense of euphoria, muscle relaxation, and sleepiness in the user of the drug. Since THC is absorbed within seconds into the bloodstream, the effects of the drug can occur quite rapidly.

Other short-term effects of THC include an increased appetite, blood-shot eyes/redness of the eyes, and delayed motor skills. Long-term effects of chronic use of THC may cause issues such as cognitive impairment and may even affect one's memory.

The good news though is that these effects seem to wear off after discontinuing use of the drug. There also doesn't seem to be any residual effects or complications associated with long-term marijuana use once one has stopped using the drug for a certain period of time.

Marijuana use can be associated with certain side-effects though and these may include:

  • Paranoia
  • Increased anxiety
  • Panic attacks
  • Delusions
  • Hallucinations (believing one hears or sees things that are not present)
  • Violent behaviour due to the psychotic features

Fortunately, these can also wear off relatively quickly once the drug is discontinued but immediate medical assistance should be encouraged if these signs carry on without the use of the drug.

Dangers of combining marijuana with divalproex

As can be noted by the side-effect profiles of both drugs, central nervous system and psychiatric effects feature dominantly in both situations.

Therefore, one can ascertain that combining the use of marijuana with the intake of a medication such as Divalproex will increase the likelihood of experiencing adverse reactions such as fluctuations in the user's mood, psychosis (delusions and hallucinations), paranoia, and even a decreased level of consciousness which may be a life-threatening situation.


The message to take away from this article is that one should try to avoid combining the consumption of marijuana, in whatever form the user chooses, and the use of drugs such as or similar to Divalproex in order to avoid experiencing the mentioned problematic signs and symptoms.

Anyone who finds themselves in a situation where they have been using marijuana and have become dependent on the drug, because discontinuing it will result in withdrawal symptoms, should discuss stopping the use of marijuana with the doctor who would like to prescribe the Divalproex in order to help the patient to stop using the drug. 

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