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My father is 65 years old and he suffers from a heart condition. Beside that, he has the problem of the increased possibility of thromb creating. I am trying to be informed as much as possible and I would like to know if it is true that hypoxia is the number one problem in stroke.

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Increased coagulation and thromb creation can easily lead to stroke occurring. But with the regular use of anticoagulation therapy (aspirin for example), the risk of stroke is reduced. Hypoxia happens when thromb obstructs the blood vessel in the brain and disables the oxygen flow-ischemia happens first and if the problem persists, tissue necrosis happens.
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