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Hi... I just ordered HCg the drops... I wanted to talk to you maybe you can contact me.... does it really work? Is it hard to stay at 500 calories a day and did you keep the weight off after?
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If you have gained weight cos of methadone I Strongly reccomend you read every word I post below about OPIAD as it may change your lives! and no I’m not selling anything, just hope to help if u may have this little known condition that 90% of opiate users unknowingly have!
I have been struggling with my weight since I increased my 40mg of methadone to 100mg 5 years ago. I was always a perfect weight (45kg but im 5 foot only) but I doubled this to 90kg within 4 months when i increased my dose. I was pregnant at the time which was why I was needing to increase my dose, and my dr didnt tell me that my weight gain wasnt normal despite weighing me every visit so I wasnt concerned. after I had the baby I couldnt stand up for more than 20 seconds since I was now carrying 45kg I wasnt used to, until a year or so later when I had finally grown calouses on my feet. I did everything to lose weight, barely eaten in 5 years, had one optifast shake a day and no other food at all for over a year but didnt lose 1kg!!! a year ago my periods stopped too and I am freaking out as I really want another child one day and im already 34.
I have only just linked the weight to my methadone recently, as my partner has gained 40kg or so extra during the last year when he doubled his dose from 100mg to 200mg due to a relapse (he was normal weight on 100mg and no drugs for ten years). so now will be trying to go down as much as I can. I dont think il ever be able to get off it though. Doing a search I came accross many many women in similar situations, and discovered we probably have opiod induced androgen deficiency (OPIAD), which is basically a lack of sex hormones caused by longterm opiate use, which has many many side effects. Most of the studies and diagnoses have been on patients on methadone for pain, for users our doctors just assume all these sympotms we complain of are due to being ex users, but pain patients must be taken more seriously. I will post main points on what Ive discovered about this condition from a dozen articles I read below, but do your own searches too.
If you have gained weight cos of methadone I Strongly reccomend you read every word I post below as it may change your lives! I am hoping it might mine, I only found out about this disorder last week. I am now getting a blood workup to test for a zillion hormones and hopefully this is what I have because I have all the symptoms, and so does my partner and we had no idea why, not just wieght gain and knowing theres alternatives such as testosterone replacement rather than just stopping the done which I cant is hopeful.
Anyway do some research and talk to ur doctors about OPIAD, it seems like 90% or more of us likely have this hormonal problem and arent told about it. pain patients on opiates are meant to be tested for testosterone and other hormones every 2 years to avoid opiod, and be told about the risk before going on it. but we arent even told it exists!I hope this might have helped some of you and hope it helps me and my partner. It is great to know I am not alone, and my symptoms are so common in people on MMT.
opioid-induced endocrinopathy
Opioid-induced endocrinopathy is one of the most common yet least often diagnosed consequences of prolonged opioid therapy.Opiod-induced androgen deficiency (OPIAD) is one of the most common results. The inadequate production of sex hormones caused by OPIAD is referred to as hypogonadism. Various studies have reported rates of hypogonadism between 64% and 94% in men using chronic opioids. when opioid dose ranges exceed 100 - 200 mg of oral methadone.Women may experience amenorrhea or oligomenorrhea as well as early menopause In another study, periods had stopped in (67%) women, and compared with women with chronic pain who did not use opioids, concentrations of luteinising hormone, follicle stimulating hormone, oestradiol, and adrenal androgen were considerably lower in both premenopausal and postmenopausal women.
. Men and women may experience decreased libido, osteopenia, osteoporosis, fatigue, depression, impaired immune system, decreased muscle mass, and increased fat deposits
In a cohort of patients who received opioids for 2 years, decreased libido or impotence was found in 96% of men and reduced libido in 69% of women.
.OPIAD is dose dependent with more severe results from higher opiate doses
Hypogonadism with opioid use is dose-dependent and occurs quickly. Patients receiving 100 mg to 200 mg of methadone equivalent for 1 month are 50% to 100% likely to develop some degree of OPIAD.
Signs and symptoms of hypogonadism
Fatigue and decreased energy and vitality
Depression and irritability
Decreased libido
Erectile dysfunction
Decreased lean muscle mass
Increased visceral fat (Visceral fat is body fat that is stored around the stomach associated with increased risks of a number of health problems including type 2 diabetes.)
Decreased bone density
decreased hair growth
Anemia
Decline in cognitive skills: concentration and memory
Sleep disturbances
Amenorrhea (loss of period in females)
early menopause
Flushing and sweating
Loss of libido
Infertility
Depression and anxiety
Low energy levels
Osteoporosis and fractures
Treatment Recommendations
The Endocrine Society recommends that hypogonadal males be treated with testosterone to improve sexual drive and performance, increase bone mineral density, increase muscle mass, and decrease fat mass Female pain patients (and dont forget us poor addiction patients!!!!) with low testosterone levels may also require testosterone replacement.
DHEA
DHEA may be used in women diagnosed with OPI-
AD. It is available as an over-the-counter supplement in
most pharmacies and health food stores. Due to lack of
regulation of these supplements by the FDA to comply
with good pharmaceutical practice, the actual content
of DHEA may be highly variable from one supplement
to another (52,56). It is recommended that women
take a 50 mg dose of DHEA daily if this is to be used
as ART(66). Follow-up laboratory evaluation of DHEA
levels is recommended and will help further guide ad-
justment of this therapy (
In women with established adrenal insufficiency, studies find 50mg DHEA corrects low serum concentrations of DHEA/DHEA-S, and brings testosterone into the “normal” range. With one recent study finding “DHEA treatment significantly improved overall wellbeing as well as scores for depression, anxiety, and their physical correlates. Furthermore, DHEA significantly increased both sexual interest and the level of satisfaction with sex.”(5)
Weakened immunity, mood imbalances, anxiety, fatigue, increased fat mass, and poor memory function may result from DHEA deficiency. As a vital steroid hormone, DHEA (Dehydroepiandrosterone) is the precursor to other hormones, like testosterone and estrogen.
if anyone has spoken to their dr about this or gotten some blood tests done Id be interested to know how many of you do have low testosterone and OPIAD. I am just so happy to find this thread and know that I am not alone. I have been thinking it was the methadone for months but my chemist said noone else here is overweight and shed never heard of methadone making u gain weight. Im glad i am right and ive finally pinpointed the cause after 5 years!!!
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