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The native American herb echinacea has been a favorite for fighting winter respiratory infections for hundreds of years. Used in teas, tinctures, and capsules, this prairie plant has true believers and fierce defenders. What about science?

A staple of herbal medicine for colds and flu fails another test

The answer depends on whether you are talking about Echinacea purpurea or Echinacea angustifolia, and whether you are talking about a pill, powder, alcohol-based tincture, alcohol-free tincture, juice or capsule, whether the product is made from roots or from leaves, whether you take it before infection or after, and what else may be in your stomach when the herb hits your digestive tract.



The most recent study appears in the journal Annals of Internal Medicine. In the study, 719 residents of Madison, Wisconsin aged 18 to 80 who already had the early symptoms of a cold were told to do nothing, given an inert pill that contained no echinacea, or given pills made from a preparation of echinacea root made by MediHerb, an Australian natural products company. Volunteers in the echinacea group took 10,200 mg of the herb the first 24 hours and 5,100 mg of the herb a day for the next four days. The results?
  • Users of the herb scored an average of 236 on the Wisconsin Upper Respiratory Symptom Survey, users of the placebo, 264, and participants who did not take anything, 286. Users of the herb had fewer colds symptoms, but the difference was not statistically significant.
  • Users of the herb had colds that lasted an average of 6.34 days, users of the placebo, 6.87 days, and volunteers who did not take anything, 7.03 days. Users of the herb had shorter duration of symptoms, but the difference was not statistically significant.
The scientists also measured production of an inflammatory chemical known as interleukin-8, or IL-8. In users of echinacea, the average concentration of IL-8 was 30 ng/L, in the placebo group, 58 ng/L, and in the take-nothing group, 70 ng/L. Echinacea users had lower levels of inflammatory chemicals, but the data analysis concluded the difference was not statistically significant.

Is There Other Evidence Echinacea Really Works?

This latest study, of course, was not the first test of echinacea for colds, flu, infections, or inflammation. There are over 800 peer-reviewed, published studies of echinacea in the medical literature. Despite over 800 tests, many of them yielding results like those above, and centuries of successful use, one expert opines "Findings of efficacy for echinacea are strictly preliminary." However, other studies have concluded:

  • Echinacea purpurea root, in the product Echinaforce, prevented infection with H1N1 in laboratory studies.
  • Echinacea pallida root, in a study at Iowa State University, was found to suppress all markers of inflammation.
  • A study at the University of Washington found that echinacea is safe for children aged 2 to 11, although about 10% more children in the echinacea group developed itch-less rashes.
So why are there negative results in some studies? The answer seems to be that there are not enough people in any of the studies to establish statistical significance (and that may be the intended result of the research designs). Sure, echinacea makes people feel better and reduces inflammation, but we can say it's not a statistically significant effect, the researchers tell us. And it also makes a difference which product is used for which purpose.

If you are concerned about H1N1 "swine flu" or an outbreak of bird flu viruses, your best best is to take an Echinacea purpurea root product like Echinaforce. If you are treating a cold in a child, try to give your child an echinacea tea, made by pouring hot water over Echinacea angustifolia, Echinacea pallida, or Echinacea purpurea root, or, even better, a combination of all three kinds of echinacea. Sure, part of the healig effect may be the warmth and moisture from the tea itself, but the idea is to get well! Otherwise, make sure any product given to a child is alcohol-free. To be on the safe side, no one who has an allergy to ragweed or who is on steroid treatment should take this herb.

Sources & Links

  • Pleschka S, Stein M, Schoop R, Hudson JB. Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV). Virol J. 2009 Nov 13,6:197
  • Senchina DS, Wu L, Flinn GN, Konopka del N, McCoy JA, Widrlechner MP, Wurtele ES, Kohut ML.Year-and-a-half old, dried Echinacea roots retain cytokine-modulating capabilities in an in vitro human older adult model of influenza vaccination. Planta Med. 2006 Oct, 72(13):1207-15. Epub 2006 Oct 4
  • Photo courtesy of Steffen Ramsaier on Flickr: www.flickr.com/photos/steffen_ramsaier/4817272585/
  • Photo courtesy of Steve Kocino on Flickr: www.flickr.com/photos/stevekocino/3961086921

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