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YES IT DOES CAUSE DEPRESSION, that is the reason i ended up on the internet late night trying to see why i feel like my whole life is ending when i have nothing in my life to be sad, or upset about at the moment. Everything is great with me.

Im nearly working my way into Medical school at USC and things like this, is what drives me.

 Now that i know this is a FALSE temporary sense of Depression it seems that helped with my mood almost instantly. It can be a mind thing.

Everyone experiencing this should remind yourself that this is a False sense of depression from this medication and that everything is gonna be alright.

Just Pray, and say to yourself "By his stripes I am healed". The devil is a LIAR !!!

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Oh my God this is exactly what's happening to me I can't believe this stupid doctors when they give people some stuff like this cause they don't care they just want money ..I just throw all that nasty Allegra pills on the toilet I feel soooo depressed and life black out in my eyes
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So sorry about your loss.
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Yes I have been taking for 3 days. I found myself staring into nothing and obsessing about everything becoming very depressed and crying a lot by day 3. I also had pain in my back muscles. I also had swollen lips and face but am only just realising that was a bad side effect. I thought it was my symptoms
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I have no scientific proof other than my own experience but I believe it does. I take Claritin and have been feeling depressed/down. I stopped taking it for a couple of days because i couldn't afford to purchase any until pay day. I didn't make the connection until I started taking it again after not taking it for 6 days. It hit me on day 2 that I was going "down" again so I stopped and having been feeling much better emotionally. I suggest speaking with your local pharmacist and see what he/she has to say. Take care!
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I knew something OTC eventually was causing my depression, lethargy. First, it was Unisom Sleep Aide a powerful anti-histamine. I quit taking due to developing a resistance and my depression lifted. Then got nailed with seasonal allergies and started 24hour Alegra. The result was severe depression, lethargy and so suicidal I had a plan to end my life. I already am on an effective antidepressant but "suddenly" did not work? The entire change in my behavior, mental deterioration, etc were caused by antihistamines. Unfortunately, the clinical trials are short on Alegra and these kind of sxs do not show up in Manufacturer's Information or a PDR. What meds have I not reached out to the internet forums/message boards, or available a post study for help? Clinical trials of any med are short and hopefully find post studies or as this a forum. Doctors do not think out of the box.
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Yes! A doctor told my son to start taking Zyrtec for some allergy problems. My son started taking them and couldn't stop. Every time he tried, he would have terrible itching especially on his head. He couldn't sleep so we would put him back on. This went on for 3 years. His mood got worse and worse and he was impossible to wake up in the morning. We finally realized that he was very depressed. When he nearly jumped out our 8 story window because we were trying to wake him up, we realized something was very wrong. I searched Zyrtec and depression and I couldn't believe it. It seems along with the itching withdraws, depression is a common side effect. He tried another similar product and the depression got even worse. I saw some studies saying over 10 percent have depression on Zyrtec and very few get over it. He, like some studies suggest, has not improved much at all over the past 3 or so years. He is trying to go to college and hold a part-time job, but can't do either due to the depression, anxiety, and insomnia. Why weren't there any warnings? My son's life has been ruined by this drug and you can still buy it and eat it like popcorn. Does anyone know of a way to get past the depression Zyrtec causes?
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Your story is both heartbreaking & comforting! Doctors can easily be incorrect & loosing years of a happy life seems to be the result for the patient :/ Please know that by sharing your story you comfort others who had to fight for a medical answer & be told countless times they are wrong. Way to be your own health advocate. Thanks for sharing :)
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Sorry to hear. My brother committed suicide by jumping off a 15 story building because of Zyrtec on May 17th of 2013. This has crushed my mind, heart, spirit, and soul every single day so far. I have a burning hate towards the pharmaceutical industry.
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I have gone on this med this year for allergies and last year as well, and I believe it absolutely causes negative mood changes, nightmares, etc.  I am a clinical psychologist and pretty self aware and 48 hrs. after stopping feel noticeable better (even with my allergy symptoms).  Now trying butterbur for allergies because sick of the side effects of these kinds of meds.  

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I am so sorry for your loss. I have no doubt that Allegra could have been what caused your daughter's depression. I am so so sorry. My heart aches for you and your family.
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I know these threads are old but I came across this last night. I have been taking Allegra for about a week and half and have been feeling extremely depressed. I didn't put it together right away ...as I was trying to figure out what I was doing different Allegra was the only thing that was different . So I decided to look it up and see if anyone else was feeling like me. Here I am. I have been reading everyone's comments and would just like to know if any of you had some anxiety /depression before taking the Allegra. I have a little on a daily basis but this has just put it through the roof. I don't even want to get out of bed . It is very scary. I am stopping the medication immediately but just would like to know. I have taken plenty of allergy meds in my younger years with absolutely no side effects. And now I just feel crazy
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Don't flush meds. It pollutes the water supply and ends up in the food chain.
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I've been on Allegra and Flonase for almost 2 years now. My allergies are bad everyday and the two are the only ones that seem to help me. But I've noticed that my mood has changed, I feel dull and depressed... And I kept trying to figure out what had changed I really had no reason to feel that way. I just didn't even want to leave to house I feel like a hermit. I used to be very outgoing. Now I avoid social situations like the plague. The more I read these comments I feel confident that Allegra and Flonase are responsible for this. Starting tomorrow, I'm going to quit taking both. I really hope that this helps! No matter how bad my allergies are, I'll deal with it if makes me feel more hopeful again.
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I started to take antihistamines in 1993 due to severe itching, at the same time I started to become anxious and depressed. I put these feeling down to whatever was causing my itchiness. Gradually over the years I became more and more unhappy and anxious, constantly have feelings of isolation, became really self conscious and forgetful, found it increasingly difficult to hold a conversation, felt my thinking and speech being impaired, have constant headaches and became an introvert, always in my own little depressed world. Despite all this I just got on with my life, got married, have 2 children,a nice house and a good job but still feel deeply unhappy. In 2008 I had to change tablets to fexofenadine due to a change in my job. This week I had more allergy tests and had to come off my tablets for 3 days, I didn't feel any better but when I resumed the fexofenadine I had the worst migraine ever. For the first time I researched the side effects of antihistamines and it has suddenly dawned on me that all of the feelings I have experienced over the last 20 years could be because of a drug that was supposed to make me feel better. I have now vowed to never take one of these ever again, i just hope and pray that I haven't done any lasting damage to my mind and once the drug has completely cleared from my body a may start to feel normal again for the first time in years! Can someone please reassure me that I can return to my old self from 20 years ago?!!
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