.Guest wrote:
Suboxone blocks the opiate receptors in the brain making Heroin useless. But, you have to be in FULL detox from H before you take your first dose. Also, Cocaine does not make it so the suboxone doesn't work. Its two different systems. If you are on H, get help before its too late.
So youer' saying that cocaine doesn't make it work? What do you mean by two different systems? I don't understand what that means. Can you explain?
So I'm gonna answer a few peoples questions in this post starting with the one quoted above. Sorry for any spelling errors, I'm writing this on my phone while I wait for laundry to finish. And although I do have a fair amount (ok a lot, or at least a lot more that I probably should have :P) of experience with all of the substances in question here remember that I did not spend 6 years of my life becoming a doctor so if something seems off, please feel free to correct me! Either you'll be right and people will be better informed, or wrong in which case ill probably rub it in your face forever but either way everyone wins.
To start it is important to understand exactly what suboxone is in order to know how it will affect the drugs you take. Most people are unaware that suboxone is in fact a combination of two drugs in one pill/dose. Suboxone is a combination of the drugs buprenorphine and naloxone, in a ratio of about 4:1 bupe to nal. Bupe is an extremely powerful synthetic opiod and does several things. The bupe helps keep people who are taking subs from experiencing the majority of widrawal symptoms because it is an opiate itself, however one that has been found to work on the opiate receports differently from h, percs, purple drank you name it. Google this if you want, its not really important for answering these questions. Keeping in mind that it is an opiate however, it is possible to feels some opiate like effects when taking it. However an individuals opiate tolerance plays a major role in the effects they feel such that someone with no tolerance at all could easily become almost uncomfortably loaded off of as little as 2mg. Whereas it is not uncommon for addicts in recovery to need more than 16mg or more a day just to keep their withdrawals manageable.
The other compound in suboxone, naloxone is responsible for the rest of the drugs effects. Naloxone by itself is actually used in hospitals and elsewhere to treat, and actually reverse opiate overdoses. Without getting too sciency on everyone (the actual processes are more complex, again see google) naloxone will bind to the opiate receptors in the brain and it binds to then so well that it will basically "kick out" almost any opiate that is occupying that receptor, heroin included, and is very hard to "kick out" itself. By occupying the receptor sites (it will bind to/those that the bupe doesn't) it does two key things: it "tricks" the receports into telling the brain that they are occupied which can help reduce ones desire to use, and it also prevents other opiates from binding to those sites, which I will talk about later. These effects usually last 48 hours or longer, due to either an extremely long half life or their astounding binding abilities though I can't actually remember which of those it is atm (could be both too? Google it :P). There are only two opiates I know of that can bind better than naloxone, those being buprenorphine (no suprise there) and fentanyl.
So now to relate this back to all of the unanswered questions on this page. Cocaine does not affect the opiate receptors and will therefore not interfere with suboxone use in treatment. The two different systems mentioned above are basically just that: coke gets you high one way and opiates another, and so even with the opiate rout closed off the systems in your brain which use cocaine are left unaffected. SWIM was able to use coke regularly while on suboxone and experienced no dimished effects from either.
To our Croatian friend and everyone else wondering about the interactions between heroin and suboxone there are several things I can tell you. First the reason it is recommended that you wait several days from your last dose of h until your first dose of sub, and why people who do not wait describe feeling like the sub made their withdrawals come on far more rapidly is because of the naloxone in the suboxone displacing the dopamine/other endorphin releasing heroin molocules from the opiate receptors and replacing them with the inert naloxone. This process of heroin leaving on its own would usually take 2-3 days, and be much more gradual than 2-3 hours and is the main reason why people recommend waiting so long to start suboxone; basically a comfort issue as the effectiveness of the suboxone does not really change.
As far as taking heroin while on suboxone you might as well save your money and send it to me ;). You will feel something on the range of nothing to absolutely nothing from the h due to the naloxone and buprenorphine occupying the receptor sites in your brain. If you take suboxone regularly then you would have to wait 2-3 days at least before being able to feel the effects of other opiates, so taking suboxone in the morning would make taking heroin in the evening pointless, and would serve only to increase your tolerance more as your body will still have to metabolize all of the heroin too. SWIM would recommend that if a person took suboxone too soon after doing h and was experiencing terrible withdrawals that instead of trying to take more heroin to end the withdrawals that they instead take more suboxone because of the buprenorphine in the suboxone. There is more bupe in the subs than naloxone, and the bupe can bind almost as well while in the presence of naloxone in the brain so short of finding somen medical grade fentanyl this would be the best/easiest way to lessen ones withdrawal symptoms in SWIM's opinion at least. By using more sub instead of going back to simply using you would also be that much closer to breaking the cycle and getting off of opiates entirely :D.
My laundry is done and so I must go now but I'm following this thread so if anyone has further questions on the topic post them here and ill reply when I can.
Good luck and peace be the journey
The General
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Thanks a lot all.
RM
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i wanted the doctor to read this and respond please! i am getting ready to leave the country for a couple of months and need to stop using H NOW.
this is my story-i have been working really hard and have tons of pain from lots of accidents and asked a friend if he had anything that would help...i wasnt sure what it was...but i found out it was H. i LOVE it-it makes me superwoman and i can do anything but the fact is i need to stop (its only been a few months since i first tried it-damn it!) anyway another friend went out on the streets and found me the 8 mg of subox. i got 6 of them but plan on getting 6 more this week so by sunday i can be done detoxing (i fly on sunday)
my questions are (cuz nothings real clear here with all types of different addicts and their personal experiences) this is mine.
i am doing about $60 worth a day (its whit and i know the content probably isnt very high of H) i have vicodin and valium...oh and ambien for the detox. how do i do the detox...WHEN should i stop the H and start the sobox? should i take anything else to help-ie the valium,vicodin or ambien?
i never thought i would go here with the H cuz the vicoden works and i actually had kicked that several months ago after taking and average of 1kmgs per day...i will keep using that but not everyday and never more than 1 norco a day.
the H takes away all my pain and i feel like superwoman but then the pain is back the next day :-(
I NEED help asap! I am so grateful for any good advice and would prefer a doctors response. remember i got the sobox off the street-its real...they get from hospital down the street and then sell for $10 on the street. i wish i could just call a doctor and have them prescibe it. i do NOT plan on taking more than a dozen sobox period! i am leaving where the source is next door so i wont have it around me and i will have 2 months to forget about it and relax!
namaste!
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Guest wrote:
does cocaine injection effect the suboxone? I heard it causes you to get withdrawls or makes the suboxone stop working.
Absolutely it does. Cocaine, heroin, crack, and virtually any painkiller can cause suboxone to stop working properly if i'm not mistaken. That's what my understanding is. Can anyone confirm this? That's what I have heard.
I stress this w/ great emphasize b/c I am a sniffer who also cuts their cocaine w/ lactose prior to ingesting, so the intensity for other will increase. B/c Suboxone has Narcon in it which is similar to an upper the cocaine clashes w/it & gives off the effects of straight speed once it hits. It goes straight to the heart & the next thing u know u have chest pains. If & when u cough, u feel the sensation throughout you upper body, arms & head. The heroin will not balance it out & before you realize it, you've ingested several bags too many of that too which makes you sick in its own way. So know your nausas, vomiting, when the explosion goes off in your head & you start sweating profusely. Combine all of these symptoms together & happening all at once of which the only control you have is trying to keep your body from falling apart & then throw in a reaction of fecal matter on top. It happened to me & b/c the addict in me said it was just a one time thing being the first time, I tried it again a few weeks later. Imagine what I described being twice as bad /b/c your bodies muscles weaken especially the heart & does NOt bounce back so easily. The caution & fatality warnings are very true, I am in the process of testing by a cardiologist b/c (Being someone who has never had heart problems) my primary physician did an EKG & it showed that somewhere during the course of my addiction , greed,& stupidity, meeting up & convincing my that "I Got This" I was rewarded w/ a mild heartache that I wasn't aware of but left me w/ the a reward for my efforts Of frequent symptoms as as reminder. Oh, just so none of you so called hard core users maybe thinking that person propably was weak or didn't use drugs long etc. Not only have I been getting high for over 25 yrs, I am a poly substance abuser, who b/c I have Bipolar Type 1 ( diagnosed long before started using) use to chew as many as 10- 2mg- xanax per day & nobody would ever know it b/c it stopped working after awhile. As such, I could venture to say I have the tolerance of a Horse! I consider myself blessed to have made it through that experience, if you think you're lucky go ahead but consider this. It just may not be the day!
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i wack 80 of oxys n feel it da full affect but
i was just wondering if someone could tell me if i had a wack of h now will i feel it???
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make a suboxone foiley! thats how. ha. mix n a little baking soda add 1 drop of water n spread it out to a nice even paste and moke it! ooh it feels so good ha
people come onto this site for concerns regarding help with their substance abuse problem. this is not the place to encourage, make jokes and/or or ridicule anyone. If you appreciate that b/c you are not ready to deal w/ your problem, then you have NO business being here. If can appreciate and/or respect that b/c you are NOT an addict, then you have NO business being here!
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