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It is found in so many products, that I do not dare wash my hands with any unknown soaps. I only use Tone™ brand bar soap. I went to dermatologists and was prescribed Clobetasol Propionate .05%. It works for me.
Hope this helps.
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I have had this problem for ten years now. Only on three fingers. Suffered from eczema as a kid. Bandaids and gloves seem to help somewhat but are difficult in daily life. Tried steroid creams and those didn't help. The only thing that helps is to get acrylic nails. I hate doing it because they are costly and going to the nail salon every two weeks is a time suck, but I can't pick them then and they heal up. Then I will stop for awhile, it will come back within a few weeks, I will suffer for awhile and then head back to get the nail tips again.
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There is no known cause for what I have. My hands are in no caustic or strange substances, and I have tested negative in a standard allergy patch test. And while I state that this has been bad for a couple of years, I have actually had smaller patches of it for much longer. Until it got really REALLY bad I was able to ignore it.
One of the earlier treatments I had tried, and there is nothing I have not tried, was Psoriasin, a coal tar ointment that also had no effect. Bear in mind that I saturate the affected areas and cover the fingers with a finger cot over night; I may do this during the day as well if things are really bad. I have used Clobetasol in conjunction with Psoriasin and at best gotten half a day's relief.
I my endless searches for a solution I came across a scholarly article that stated specifically that the action of Clobetasol had been significantly improved when used in conjunction with DMSO, and that this had been applied in a situation similar to mine. No derm or other doctor has ever mentioned this to me. I can no longer find that article, but it's out there. Bear in mind that DMSO is a carrier that transports substances across the skin barrier deep into the flesh, and my thinking was that this transport mechanism might make some sense. I had some DMSO on hand and had actually been thinking about giving it a go, just to see. So I saturated a couple of problem fingers with DMSO and then layered on a good amount of Psoriasin (you're looking for 2% coal tar ointment, MG217 is another), worked some more DMSO into that, covered the fingers with a cot overnight and... next day I was better. I repeated the process and... next day I was even MORE better, and I had been starting with a vicious condition on my hand. I worked some Clobetasol in here and there, but the coal tar worked fine on its own. I continued to do this for a week, and in about that amount of time of repeated DMSO / Psoriasin treatment BOTH OF MY HANDS WERE BETTER. This was the first time In two years that I wasn't looking at my hands and seeing deep cracks, raw flesh and open bleeding wounds. As I write this I have one tiny crack on one of the fingers, which I will continue to treat; the rest of the hands are sealed tight and actually look pretty darned good.
I must emphasize that it appears that REPEATED application of the DMSO / Psoriasin is necessary to get results; if you just apply it once or twice and give up you'll get no where. If you have a really large area to treat get a little spray bottle for your DMSO, it seems to spray pretty well. There are both gels and liquids of DMSO; I've only used the liquid but the gel may be very appropriate in this application. Also, I poured out a little DMSO into a cup and mixed the Psoriasin around in it, then just applied that with a Q-tip to the affected area and let it settle in without covering it with a cot. This is easy to apply throughout the day. That one really works, and the relief can be almost immediate.
I do NOT know if this is a cure or just long term palliative relief, nor do I know how this will work for each specific case. I will personally continue to treat as necessary, but right now It's been a week and only one small crack on one finger. Coal tar / Clobetasol / DMSO appear to be the winning combinations, but someone else might find another combo that works. I'm not sure about straight DMSO with no other substances; the gel may work well on its own, but I know that it works with coal tar.
So if you are desperate, you need to try this one, and I'm quite serious. Then ask your derm why they never mention DMSO as a potential treatment for this one.
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