Overview
Valium, which is the first brand name for the benzodiazepine drug diazepam, is prescribed to patients for its sedating and calming effect. The medication is used to manage conditions such as:
- Acute anxiety.
- Severe muscle spasms.
- Insomnia.
- Seizures.
- Symptoms associated with alcohol or even benzodiazepine withdrawal.
- Restless leg syndrome.
- Sedation for performing certain medical procedures.
- Retrograde amnesia in those undergoing medical procedures so that they don't remember any discomfort or pain.
Side Effects
It's important for patients who use Valium to be aware of the possible side effects associated with the medication as these will usually occur if the dosage or frequency of the drug is increased for whatever reason.
Long-term issues associated with Valium may include tolerance to the drug which causes the user to take more of it to experience the effect of the medication. This can lead to dependence where trying to stop using Valium may lead to withdrawal symptoms and this can be followed by addiction to the drug.
Overdose
Tolerance, dependence, and addiction are mentioned because these can lead to an individual on Valium taking more of the medication than what is prescribed by the patient's physician.
If any of these signs and symptoms, or the mentioned side effects, occur in those who use Valium then it is suggested that these individuals present to an emergency room to receive immediate medical attention.
A Valium overdose is not usually fatal but it is considered a medical emergency requiring treatment with an antidote such as flumazenil to reverse the effects of the drug and is used in cases where the user experiences problems such as respiratory depression or severe hypotension. The patient may need to be intubated and receive artificial respiration since the effects of the Valium can last for days.
Lethal Dosage
The lethal dose of Valium in 50 percent of the population is 720mg per kilogram in mice and 1240mg per kilogram in rats. A human being would have to ingest a massive amount of Valium or any other benzodiazepine alone for the drug to cause a fatality in humans. There have been cases where patients ingested between 500 and 2000mg of the drug, 50 to 200 times the maximum prescribed dosage, and they were discharged within 48 hours of being taken to an emergency room without experiencing any major complications.
- www.ncbi.nlm.nih.gov/m/pubmed/29442611/
- Photo courtesy of SteadyHealth