After a gap of 2 years I restarted a course of bladder installations, for my PBS/IC I will now have one every 2 weeks as I have been in a lot of pain with this chronic condition. There seems to have been a lot more research during this time for this condition. The updated leaflet for Cystistat (The product inserted into the bladder) is much more informative now., it can be found online. Previously my consultant disagreed with me that diet affected it, but now they say, coffee, citrus artificial sweeteners, white wine and highly spiced food (this last one I always noticed exacerbated my problem) I was helped somewhat with a course of these instillations before but my problem returned with a vengeance again. I have found applying a hormone cream like Gynest twice a week to combat dryness, also helps. Hope this information has been of use. Regards Maureen