I have tried diphenyldramaine (benadryl) in a combination with 2c-i. The 2c-i allowed for very colorful visuals, so watching TV with this combination was insanely fun. Although the dry mouth is definitely horrible and the next day you can barely stay awake, it’s worth trying and can be fun.
My good friend has done both dramamine and benadryn a couple times and found the trip to be interesting but the feeling this gives one was not very pleasant and causes a lot of restlessness. He started noticing visual distortions and if he focused for a second in one spot it appears that some kind of vapor was coming off of everything.???? It appeared that certain things would be moving when they weren't and at one point he thought a lot of ants were crawling on the ceiling. I guess it can be fun with benadryn but be careful!