In 1993, Neurontin was approved by the FDA for the treatment of partial complex seizures, in combination with another anti-seizure medication. It was then marketed by its manufacturer for off-label use in treating bipolar disorder, despite the fact that there was not sufficient scientific data to back it up. A lawsuit resulted, as it was believed that Neurontin was marketed fraudulently for unapproved uses.
I have bipolar and I am on meds. I have been taking Gabapentin- prescribed by the Va for an injury I incurred from being in the Army. I usually take the Gabapenin at night before bed because it relieves some of the pain in my legs. Recently the weather has been horrible and my pain has increased so I have taken in before work at a cashier at walmart. A night ago I decided to try to forgo the meds because of the fog brain. I woke up with the shakes and when I got to work in the late evening shift I lost my marbles with a customer and lost my filter. I looked at my pupils and they were huge. I went into mania.. I came home and I was itching so bad all over my back and really everywhere. I took the gabapentin last night and I am wondering what in the hell happened last night. I am on a mood stabilizer and an antidepressant. The gabapentin makes me feel very high and I am talkative but when not taking it, it made me into a raving maniac.
Epilepsy long in remission after surgical treatment, I became an alcoholic so I finally went to a doctor and asked to be given gabapentin again as I knew the positive effect. Taking it I was able to stop drinking. I just kept taking it after that, taken it for years now at 300 mg 2x daily and it is the same as I remember. I am calmer, more social, and less dark brooding thought train. I am stable. Very slight sedative effect, but I am willing to live with that.
Gabapentin works for me. Took lamictal once for epilepsy and had to stop due to adverse mood side effects. Intense continuous weeping panic, but my neighbor took lamictal and it calmed her down. I would say for some people neurontin works.