Hi, I’ve been diagnosed with osteoporosis for the past four years and to be honest, I’m not sure if I suffered more side effects from the therapy I got (first Boniva, then Reclast infusion last year). After Boniva I was in pain for months and my kidneys might have suffered permanently from Reclast. Now my doctor is suggesting I have Prolia, and since she knows why I’m hesitant, she did warn me about side effects mainly because I already have kidney problems. Oddly enough, Prolia might lower my calcium levels and cause even more problems. Most other experiences I read mention that Prolia causes dry mouth and related oral problems. I was hoping someone could tell me how severe can this oral complications be and how often do they happen?
Hello,
to put it simply, yes, Prolia can cause very serious oral problem - jaw osteonecrosis. It is one of the not too common but extremely serious side effects of this medication. Osteonecrosis means that jaw bone and tissue deteriorate because they are not getting any blood supply. That's why before you start Prolia treatment you need to get oral examination first, because this side effect happens more often if you have to do some more serious dental procedures or you already have conditions such as paradontosis. And there are big chances Prolia will affect your calcium levels and kidneys, so that is a very important consideration you need to talk to your doctor about.
Wish you all the best,
Nicole