I have been on antidepressants for 17 1/2 years, which is a long time. Last year (2015) the antidepressants seemed to lose their effect on me, because by August I felt really low, I thought it was to do with the loss of my mum, as she's been gone for almost 3 years, this year, I just wanted to leaves home, leave my family and to be alone.So in November I went back to my GP and he suggested I try a different type of antidepressant, so I weaned myself off of Fluoxetine and decided to stop antidepressants altogether. Since then I have felt so up and down with my mood, it's been horrible, so far I have tried vitamin B complex, vitamin D, Magnesium, and Zinc, I have had terrible problems sleeping, with restlessness, hot and tingly feet, temperature being all over the place, feeling angry, emotional, anxious, miserable, tense, you name it, and I think I've had every negative mood under the sun! Out of desperation I am now taking 5-HTP, things were OK yesterday, but today I feel like I've taken a step back, I just hope this is a blip, I must also add I am on a serotonin diet, we are now in May, and I'm wondering how much longer this is going to take for me to feel any benefit of what I am doing, I really don't want to go back on antidepressants again, I realise there is no quick fix, so I'm open to any suggestions!