I am currently on methadone 240mg a day. I dont like the drug at all. The side effects are my teeth rotting out of my head, i just had all my back teeth pulled and im waiting to get my partial for them, thank god it wasnt the front where you could see. another side effect is weight gain. i went from 112lbs to over 180lbs in a 2month period. No diet change, and i know it was the methadone because i stopped taking it for a good two months and took oxycontin off the street and 80% of the weight dropped off. I need pain medication, but I dont know how my dr. would feel about switchin me. Another thing, where i still take methadone at the time, at what dosage does it block any other opiate?