I have taken 2 benadryl and it stopped the itching. I'm stopping medication immediately now that I have done some research and found the source of my itchy palms is from taking Wellbutrin.
I had itching a lot in the first 4 weeks, I went off for a month or two and when I went on again it was fine.
I had been on Sertraline (zoloft) for almost a year for anxiety/depression. I recently switched to Wellbutrin XL 150mg once per day, because the Zoloft was making me gain weight. I started the Wellbutrin along with levothyroxine for low thyroid at the same time on April 17th and by April 19th I was itching from head to toe! I tried to deal with it, but by Monday it was driving me crazy. I reached out to my PC and she recommended stopping the wellbutrin for 1 week to see if it goes away and vice versa with the levothyroxine to see which is the culprit. After reading numerous website, and reviews im quite certain its the wellbutrin that causes itchiness. I stopped it yesterday and am still itching today. I read it could take up to 4 days or longer to leave the body, so we will see.
Does it go away ???