ive been on the depo shot for almost a month now, and I’ve had the worst cramps in my live off and on for the last few weeks. I’ve also missed my period since I got the shot a week before it was due. I keep freaking out that maybe I’m pregnant since I had unprotected sex in the first week of getting the depo but I’ve done a few tests and it always says negative. Plus I’m still on the pill since it’s helping to keep things normal, my doctor said to. So I was on the pill when I had unprotected sex.