Hi, I currently take Cymbalta and Wellbutrin and my Doctor had considered changing me to Prestig a new antidepressent just like effexor with little change. I have migraines everyday, and my Doctor told me that I was also a little high strung. Anyone take anything to make them chill out? It is not in my genetics to allow myself to slow down or be lazy. I also take topamax to prevent migraines and that stuff makes you forgetful!!! Anyway with a migraine I am pretty fussy all the time so I am not sure any antidepressant would really help. I am seeing an neuro soon maybe they can help. Thanks for an input.