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You seem to have absorbed a bit of information you don't fully understand.
Venlafaxine isn't an "ingredient found in most antidepressants" it's a specific drug (an SNRI). Zoloft is sertraline (an SSRI), Effexor is venlafaxine. Also, "causes your brain to overload with serotonin reuptake agonists" is a borderline nonsensical statement.
It seems far more likely that you got anxious because you already suffer from anxiety, and were doing something dumb and reckless like driving while high, which frankly should make you nervous.
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i've been a mostly daily smoker for a couple years. no issues, a couple bad trips here and there, but nothing i couldn't talk myself out of.
i just started sertraline (for both anxiety and depression) exactly one week ago. took 25mg for 4 days. smoked weed all those days, no issues. upped it to 50mg (as ordered by my dr.) on day five, smoked weed, no issues.
then day six. took another 50mg and smoked a small amount of weed. felt fine until around 4am and started to get a headache, light sensitivity, auras, so i went to bed thinking i was getting a migraine. for the record migraines aren't common for me, i've had like 2 my whole life and they were nowhere near this severe. also i was getting mild headaches and nausea on lower doses around 12 hours after taking 25mg, which is about the same amount of time after taking 50mg that the migraine started. this was also hours after i smoked, i was no longer high (and wasn't very high to begin with.)
as soon as i'm in bed the migraine sets in full force, i was shaky and hot/cold every other second. my heart was beating fast. i'm certain i had a fever but couldn't pull myself out of bed to check. i could only pull myself up to go vomit 3 times in a row. when i got back i was extremely restless/irritable and started tossing and turning constantly. at this point i'm just squirming and literally groaning/yelling with pain. i somehow fell asleep, woke up feeling worse around 7am. i almost considered asking my mom to stay home from work and take me to the hospital.
this may not have sounded that bad but honestly it was like a migraine times 5. i somehow fell asleep again and woke up around noon feeling drained, exhausted, off-balance, but otherwise completely fine. i skipped today's dose and am going back to 25mg for a few days. terrified it will happen again when i try to up back up to 50mg.
pretty sure smoking heavily for a week then starting sertraline/upping my dose put my seratonin levels over the top. i doubt this is considered "sertraline syndrome," but if this is just a normal side effect that's even worse imo. i never want it to happen again regardless. it's the sickest i've ever been and this sh!t (sertraline) better be worth it for me to give up the one thing (weed) that's kept me from wanting to end it for the past 5 years.
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