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Supplemental enzymes do not have a lot of value in treating insulin resistance, the underlying cause of type 2 diabetes. They can be extremely useful, however, in treating diabetic complications such as peripheral artery disease.

Proponents of natural medicine never have found a lot of application for supplemental enzymes in treating diabetes. Some holistic doctors have had a degree of success by replacing pancreatic enzymes, such as the epinomynous pancrease, as well as the digestive enzymes amylase, protease, and lipase. These enzymes can be very helpful to diabetics whose digestive tracts have become "sluggish" after many years of the disease. They help food break down even when the digestive tract simply cannot move it efficiently due to long-term damage to the nerves empowering the gut. However, far more dramatic effects can be found in some diabetics given supplemental trypsin and chymotrypsin. Here are some examples.

1. Enzyme therapy restores circulation in diabetic feet.

Dr William Wong reports the case of a Native American man in Montana, just 45 years old, who had had poorly controlled diabetes for many years so that he developed diabetic foot disease. Poor circulation had resulted in the need to amputate several of his toes, and his doctor was considering whether to amputate the entire foot. In addition to diabetic foot problems, this individual had parasthesias, that is, numbness, tingling, and loss of sensation in his fingers, hand, and arms.

As a last resort to amputation, the man's health advisor put him on supplemental chymotrypsin and trypsin in the hopes that something would work. Within two months, normal circulation returned to his feet. They regained a healthy, pinkish tone. 

The podiatrist no longer felt that amputation would be necessary. He also regained sensation in his hands, and was able to manage his diabetes with lower doses of insulin.

2. Enzyme therapy restores kidney function.

Wong also reports the case of an 86-year-old man in Las Vegas, Nevada, who had had type 1 diabetes for over 50 years. He suffered a variety of complications. One leg had become infected and had been amputated. The other leg was grayish. swollen, and prone to infection. His entire body had a grayish cast. 

As the result of a Lasik procedure to correct nearsightedness, the man had developed scar tissue over his lens that had left him functionally blind, although he could still detect light and darkness through that eye. His kidney function was beginning to decline as he had to deal with urinary tract infections over and over again.

Also as a last-ditch therapy, this man was given supplemental chymotrypsin and trypsin. His improvement was gradual, but dramatic. 

Over the course of several months, circulation returned to his leg. Chronic ulcers on the leg healed, and it regained a healthy, rosy appearance. The scar tissue over his eye began to break up so that he was able to enjoy the benefits of his laser surgery. Amazingly, he was able not just to reduce but to eliminate his use of insulin, contrary to any expectation of his doctors.

What is so special about these two enzymes?

Chymotrypsin and trypsin are "fibrinolytic" enzymes. They slow down the rate at which the bloodstream can form tiny blood clots on a scaffolding made of the protein fibrin. This action increases circulation, which relieves a plethora of diabetes-related problems.

How To Use Chymotrypsin And Trypsin Supplements In Diabetes

It is essential to understand that chymotrypsin and trypsin do not reverse diabetes. They do not substitute for diabetes medications. They certainly cannot substitute for insulin. It is necessary to continue with appropriate diet, to take medications, and to do blood sugar level checks several times a day to make sure the diabetes control plan is working. However, these two supplements sometimes can give the body the break it needs to make remarkable improvements.
 
Chronically elevated blood sugar levels can result in red blood cells and nerve cells that are covered with glycation products. Essentially, uncontrolled sugars result in cells that are cooked and caramelized, although still somewhat functional inside. Making the problem worse, the cells coated with these toxic byproducts of sugar don't get good blood flow, in part because sugar interferes with the ability of the arteries to open for good flow, and in part because the "slow flow" of the bloodstream allows blood clots to form.
 
Trypsin and chymotrypsin break up the "caramel coating" on nerve and red blood cells. 
 
They break down the fibrin scaffold on which the bloodstream can form clots. The combination of actions helps restore circulation in capillaries (smaller blood vessels) all over the body, and your body does the rest.
 
How can you use these two enzymes to fight the complications of diabetes? Here are some suggestions.
  • Never attempt to use a single enzyme to assist in healing. Enzymes work in concert with each other. As a practical matter, you will not be able to find products that are just "trypsin" or just "chymotrypsin." You will encounter these enzymes in internationally known brands such as Wobenzym, which also includes the enzymes bromelain (from pineapple) and papain (from papaya) to enhance the fibrinolytic action of the product.
  • Give enzymes a chance to work. Generally speaking, the healthier you are, the more slowly you will see changes as a result of taking enzymes. The action of enzymesseems to be tied to the turnover of red blood cells. If you are profoundly ill and your body is breaking down red blood cells in just 50 to 70 days, you will tend to see improvements more quickly as these products rescue red blood cells. Of course, you will also have more improvements to make. If you are less ill and your body is turning over red blood cells every 80 to 90 days, then you will see changes more slowly. It make take as long as three months for enzymes to make a noticeable difference in a diabetes-related condition.
  • Be careful with products that contain bromelain if you are allergic to pineapple. Don't take products that contain papain if you are allergic to latex or papayas. The combination of the enzyme supplement and a fruit to which you are mildly allergic can cause unexpected allergic reactions.
  • Ask you doctor whether it is OK for you take fibrinolytic enzymes if you are on blood thinners, such as Aspirin, Coumadin, Plavix, or Xarelto. It's not likely you will encounter problems with excess bleeding, but it is good to stay on the safe side.
Enzymes don't do most of the hard work of recovering from diabetes. Diabetics do. Enzymes only make a difference when blood sugar levels are well controlled. 
 
That means you have to stick to your diet, every meal of every day, you have to measure your blood sugars to make sure you don't need extra medications or insulin and to make sure you are not taking too much, and you should not stop taking any other medications your doctor has prescribed without consultation. If you do your part, however, fibrinoytic enzymes can make the difference that enables recovery from some of the worst complications of diabetes when nothing else has worked.

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