I've also been having these type of things happening to me within the last 3 weeks or so. I just had my Depo on the 29th of Jan of this year. I've also been having unprotected sex a lot, once before i got my shot two days before getting my next one. I've been on depo going on 4 years in April. I haven't felt this bad before after getting a shot. I've been nauseous, tired more, headaches constantly, weird food cravings (such as Pickles and peanut butter), tingly and hard feeling in my lower abdomen, sore breasts, feeling sick every morning like i just want to throw up feeling and anything that would come with a pregnancy. I've took 2 home pregnancy test they both said negative. I plan on getting the blood test done cuz i heard that could be more accurate than a home pregnancy test. So if anyone could help me let me know soon. I would like to know about what I'm dealing with. Thanks