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I am 44 y/o and I couldn't understand why I have bursts of rage, deep depression and even suicidal thoughts. I that perhaps I was premenopausal but I did't have those systems I read up on. Then I came across on an article on Depression from Cortisone shots. This opened a world of mental side effects from this procedure. I could not believe how many people have and are suffering ,like me, from "routine" cortisone shots. It makes you hyperglycemic ,it lowers your blood sugar and makes you "Crazy". Google symptoms for low blood sugar .The pain management doctor, nurse, chiropractor ever mentioned these side effects . I asked them constantly . I was rear ended in a high impact car crash and 2 disks on my neck are now bulging out. Very painful. I went ahead with one cortisone shot to relive the pain. I did not want to but being that it costs $3,000-$5,000 a shot, and my case was open, I went for it. Now my attorney wants me to get a second one to "up" my settlement. Screw that, no way will I ever get another one. This stuff is poison for you immune system , especially your liver. It will make you mental. I read that it's in your body for 1 month. I am now treating the mental and physical side effect with herbs and holistic supplements. Shame on the medical industry not disclosing to patients the mental side effects associated with cortisone shots. In America ,its always profit over people. Horrible .

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I am 44 y/o and I couldn't understand why I have bursts of rage, deep depression and even suicidal thoughts. I that perhaps I was premenopausal but I did't have those systems I read up on. Then I came across on an article on Depression from Cortisone shots. This opened a world of mental side effects from this procedure. I could not believe how many people have and are suffering ,like me, from "routine" cortisone shots. It makes you hyperglycemic ,it lowers your blood sugar and makes you "Crazy". Google symptoms for low blood sugar .The pain management doctor, nurse, chiropractor ever mentioned these side effects . I asked them constantly . I was rear ended in a high impact car crash and 2 disks on my neck are now bulging out. Very painful. I went ahead with one cortisone shot to relive the pain. I did not want to but being that it costs $3,000-$5,000 a shot, and my case was open, I went for it. Now my attorney wants me to get a second one to "up" my settlement. Screw that, no way will I ever get another one. This stuff is poison for you immune system , especially your liver. It will make you mental. I read that it's in your body for 1 month. I am now treating the mental and physical side effect with herbs and holistic supplements. Shame on the medical industry not disclosing to patients the mental side effects associated with cortisone shots. In America ,its always profit over people. Horrible .

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LOL -- Now that combination would be a total disaster for me as taking antihistamines makes me the B*tch from Hell.....
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I don't know if I am suddenly insane with depression and grief or if that cortisone shot from 4 days ago has caused this extreme emotional reaction. I know I have a lot going on with a seemingly impossible situation at hand, but getting out of pain was supposed to be a good thing. I bawled like a hysterical baby most of the day yesterday and I don't think I've ever done that in 59 years. Plus, it seems to have caused a serious flare up of rosacea and my face feels like it is burning up. All could just be me being at my wits end, but I ownder now if the Cortisone has triggered it and more importantly what to do about it.
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Omg i just want to say thank u 4 this thread. Got my injection on Tuesday and omg i just want to kill. I know im being unreasonable but arrgghhh seeing doctor tomorrow. ...at least i know im not going insane n that their is an explanation

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I had a cortisone injection into my hip 5 days ago. I've been feeling very flat, blue and exhausted since which is entirely unlike me. I'll be calling the clinic tomorrow to find the exact cortisone drug that was administered.
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I also get very depressed and anxious when getting these shots. I told my Dr absolutely never ever again would I get steroids again. He agreed and said he would not recommend them so I thought I was in the clear when I when in to get trigger point injections. 18 of them! Three days later I'm crying, depressed and anxious so u read the papers they gave me and I signed and there it is "steroids" check! Here we go. F... Never again. So sorry I don't read the whole page because they were in a hurry to keep their patients on schedule. My own fault. Miss Mary downer and depressed is all I feel.
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I get SI injections all the time for about six years now. I get really agitated very easily during the first three days to a week, I hate it because I can feel myself doing it but can't rationalize why. I also have terrible sunburn like rashes on my face and arms, I can't sleep, get heart palpitations and today after my injection I started crying and couldn't stop and I'm not a crying kind of person. But my pain is so great that I welcome all this insane behavior and side effects just to have a few months of relief. Hope this helps.
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I went in for my follow up. The doc seemed to think I was nuts. I told him how crazy I'd felt and he simply said: Cortisone can magnify any underlying depression or manic / depression.
The rest of his song and dance seemed more designed to 'teach' an observing doctor whose role made no sense to me. I have no idea why she was there -- only that this doctor seemed to forget everything that was in my file.
His new instructions are to go to physical therapy, do an anti-inflammation diet, get some cardio exercise and lose weight. I about screamed! He basically told me everything I've already been doing for 10 months.
Oh and --
And if the pain gets worse, come back for another cortisone injection.
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A couple of days after a cortisone injection in my great toe, I was angry with the world! My orthopedic Surgeon told me it was a rare reaction but I should never use a steroid again. It was an awful feeling and not one that I would want to repeat. I was frightened that I was capable of violence! I am a very easy going, laid back personality and this was so totally out of character.
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My husband is on his fifth shot and he is unbearably mean and nasty.
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Be patient with your husband . It's out of his control . Hopefully it will go away in a few weeks . Cleanse the liver , have him drink lots of water ( alkaline is best )and take supplements for the liver .
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Look up low dose naltraxone
It works. I'm on it for my autoimmune condition and it has changed my life.

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Hi, Ive just had as at Sept 16, a injection into my hip using xray for postioning. wow I couldnt believe the effects it had on me, I went from using a stick to walking normally, no pain. I am so happy. Not sure how long this will last. however I googled this side effect as the first week I felt way to good, but felt like popping out of my skin, sleep was harder, but addressed. Now I tend to blow up, poof...and I am not like that and listening seems harder. I agree it does affect your tolerance levels.
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Got a cortisone injection for neck pain and stiffness on the 18th.
First hour: panic attack.
First day and night in general: anxiety, heart palpitations, tremors, insomnia, sweating, impatience, inability to control emotions.

Ever since then: depression, pain and fever-like feeling in the whole body, behaving like a completely hopeless being, no hope of life, spells of extreme sadness, and of course, the stiffness and the pain in the neck that it was supposed to treat has returned!

All this, despite the doctor being told in details in August or so how a short course of Prednisone last December caused me so many issues. After injecting, she answers my query by politely saying, "Ah´ it´s nothing; just some cortisone."

My poor wife! Has had to put up with so much of the constant nonsense that I´ve been saying. She´s been trying so hard to cheer me up, to make me smile, but the only topic that I can think of is how long these side-effects will last. This is getting horrible! And unlike others, I wouldn´t asking you lot as to how long this can last, because I know myself well and side-effects of medicines last longer in my body.
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