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Spice, fake weed, K2 — whatever you want to call it, this drug isn't the innocent herbal mixture dealers would have you believe. Here's why to stay far away from synthetic cannabinoids.

"Spice" could just be the ideal drug — offering the same kind of high you get from marijuana, it allows you to evade positive drug test results because it doesn't contain THC, the active ingredient in weed. It may even be legal in your jurisdiction. If it isn't, though, don't worry: manufacturers constantly change the chemical make-up of the drug to stay a step ahead of the law, and the drug is easily obtainable both in person and online. 

That is, at least, what drug dealers would like you to believe. Is that really the full story, though? What exactly is "spice", how does it work, and is it safe to take? 

Spice: Not What You Think It Is

What exactly is "spice"? Or K2, Joker, Kronic, Kush, and Black Mamba? Sold in colorful packages, online often as bonzai fertilizer or incense, it goes by many names and tends to be marketed as a herbal mixture. Though it contains some visible plant materials, calling it a herbal mixture is nothing short of misleading, as the active ingredient, the bit that makes you stoned, is 100 percent synthetic. We know what it isn't, then — it isn't "all natural". What is it, though? That question is rather hard to answer. The packages, which frequently contain the logo of some kind of eye and may be sold under any of the above names as well as others, can be filled with widely varying compounds, you see. 

The compound that first became known as spice was not cooked up in a drug dealer's lab but invented over the course of perfectly respectable medical research, by John Huffmann and fellow researchers from Clemson University in South Carolina. They created hundreds of compounds that, like marijuana, act on the brain's cannabinoid receptors, publishing the results of their research in 2006. As any medical marijuana advocate will tell you, you'll experience pain relief as well as getting stoned if your cannabinoid receptors are triggered — so it's easy to see why pharmaceutical researchers would be interested. Among the formulations they invented was JWH-018, a compound that Huffman himself declared "unfit for human consumption".

When "fake weed" or "synthetic marijuana" first started appearing on the streets in 2008, law enforcement agencies discovered that they were dealing with none other than this JWH-018. 

Since that time, more and more countries around the world have been rushing to outlaw the compound — but drug manufacturers keep on altering the chemical make-up, and specific varieties of "the drug" may not be regulated at any given time. This also means that, when you buy a synthetic cannabinoid, you may end up consuming any one of hundreds of different compounds. Exactly how strong the stuff you may want to smoke is is impossible to predict! 

"Spice" isn't one drug at all then, but a jumbled mess of lab-created synthetic cannabinoids that may get you high and may help you avoid positive drug tests, but that could be far more dangerous than marijuana. 

How Dangerous Are Synthetic Cannabinoids Like 'Spice' And 'K2'?

Who Uses This Drug?

Spice and similar drugs were initially popular mainly among young and poor people who were able to buy it at petrol stations and on the internet with ease. Because spice doesn't trigger positive drug tests, the drug is also particularly popular among athletes, parolees, and anyone else who may be subject to narcotics testing. 

The Monitoring the Future survey, however, frighteningly found that as many as eight in 10 high school students had tried synthetic cannabinoids.

Spice is, in other words, now a mainstream drug with a fairly good reputation, something that kids are using. Many see "fake weed" as less dangerous than real weed, both because it's easy to obtain and still unregulated in some jurisdictions, and because they are under the false impression that they are consuming nothing but herbs. 

Those who may find the thought of using synthetic cannabinoids appealing may cite the fact that actual cannabis is increasingly laced with unknown chemicals, making the herb more dangerous than ever before. That may be true, but how does "fake weed" compare to cannabis in terms of risks? Whether you are a potential user, a concerned parent, or a teacher whose students are talking about the drug, the dangers of spice definitely need to be on your radar. 

Synthetic Cannabinoids Are More Dangerous Than Weed

Since synthetic cannabinoids act on the same brain receptors as marijuana, the effects are similar — ranging from feelings of relaxation and happiness, through impaired judgment and reduced reflex response, to hallucinations, feelings of paranoia, violent outbursts, and fear. In addition, synthetic cannabinoids may be up to 50 times more potent than weed in some cases, and much more addictive than real marijuana as well. In addition to acting on the brain's cannabinoid receptors more strongly than cannabis itself, other areas of the brain are also impacted by spice.

One study, based on data from the 2013 Global Drug Survey, even concluded that synthetic cannabinoid users needed emergency medical care 30 times as often as weed users! A year-long study of the effects of synthetic cannabinoid drugs such as spice found that as many as one in 40 users of such drugs required urgent medical attention.

These drugs have specifically been linked to risk of stroke in otherwise healthy individuals, with the highest danger of complications from using spice and related drugs being reported in young users under 17. Kidney failure and irregular heartbeats are other possible side effects, along with near-instant fevers, dehydration, and psychosis. Spice-related deaths have been reported, including 17 in Mississippi alone in the year 2015, with 1,362 serious cases of poisoning from the drug being reported in the same state in the same year.

The Bottom Line

Spice, K2, Mojo, Black Magic — whichever of the over 500 different names the drug goes by, and whichever chemical component it contains, synthetic cannabinoid mixtures are highly addictive and potentially deadly. Synthetic cannabinoid drugs are, all research into them concludes, more dangerous than natural marijuana. They are very much the opposite of what those who'd like you to buy them would have you believe, and it's important to recognize the real risks their use carries so that you can avoid using them and tell other people to do the same.

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