I've had chronic sinus problems for years, resulting in 8 sinus surgeries. Eventually, I too had E.Coli showing up in my nasal cultures and I'm writing to tell you all what has worked to kill it-because not just an antibiotic will, even Augmentin. My ENT prescribed Tobramycin which is an antibiotic that comes in a vial. You use a needle to extract 1ml and add it to 250 ml of salt water rinse. Using a 60cc syring, I squirt/irrigate it forcfully up each nostril. I do each side until I use up all 250 ml of the solution. I do this twice/day for 2 weeks and it completely kills the infection. The best part is it's a local treatment, meaning your not swallowing antibiotics systemically (thru your whole body) and dealing with side effects or becoming resistant. My ENT tried this because when I was pregnant I could not be on a strong antibiotic, but the local rinse was fine and would not effect my baby. I hope this helps all of you suffering-ask your ENT About it.
but since the surgery i have no sense of smell at all and this is scary! did any one else have this problem?
Almost E.Coli could be resistant for Amoxicilin with clav.acid and clindamycin. but should be sensitive for tetracyclins.
I noticed your post is from a year ago, but i was hoping to get some insight on how things are going with your dog and if the infection ever got resolved. I am at as loss and feel so bad for my dog as he has been going sick for about 15 months with excessive nasal mucus, coughing, gagging, and sometimes breathing difficulties as well. It was discovered that he too has e coli in his nasal cavity (after 8 or so months of trying to figure it out). So I took him to a specialist and he has been on antibiotics for several months now with some improvement, but not total clear up and still has really bad days. My regular vet tried courses of azithromycin and doxycycline, but soon after going off them, he went back to being worse and we were at square one. Specialist now has him on azithromycin, higher dose and longer time, but I don't think this is going to clear it up! He is an older dog, but until this, he was very active and happy. I would love to exchange information with you... hopefully you had successful results! Please email me at ***this post is edited by moderator *** *** posting of private information such as name, phone number or email address is not allowed in order to protect your privacy*** Please read our Terms of Use