smoking weed has absolutely no affect on me, why could this

I am the same as Joshua above.

I smoked regular cigarettes for a number of years, so I know how to inhale.

Smoking marijuana has absolutely no effect on me. And when I tell people this, they take it as a challenge, as a result, I have tried many different ways of consuming it, all to no avail (no effect whatsoever) while watching friends get totally cream-crackered!

Again, like Joshua, most painkillers don't work on me either. This is a real pain (bad pun, sorry) when I have to have medical procedures. I had an infection under my thumbnail one time and the doctor gave me what he called a ring block (an local anaesthetic injected into the knuckle where the thumb joins the palm. It didn't work, so he tried a second, and then a third. He gave up after eight because my thumb was totally swollen from the excess liquid he'd injected into it!

Having my eyes lasered was no fun, let me tell you. They gave me valium first to help me relax (no effect) and then an anaesthetic drop on each eye. The worst part was that after they finished the first eye, I knew they were going to do the same again to the second eye!

It's good to know I'm not the only one - I only wish more doctors knew about this - it would save me considerable explaining, and lots of pain!

When I started smoking weed I had the same problem, just smoke a sh*t ton, and it'll hit you. After that, you should be able to feel something from that point on :) Try to use a bong or a sinker, they work best

I had the same problem recently. I smoked with some friends and they were running around stumbling and acting silly. I was just sitting there like eh. Also, the only high I ever got was a time slow down effect. I never saw colors or laughed my ass off. And recently, I smoked it with NO effect what so ever. I smoked 2 whole buds, yet I was regular. I talked and remembered everything perfectly fine. Maybe we just have a good tolerance. I can take 3 Norco pain meds and be fine. My guess is some people have a better tolerance....

I have smoked 6 times 1 blunt to with 4 friends and 5 joints to myself I am doing it right for sure but I'm just unaffected so I just don't smoke it doesn't taste good it doesn't smell good so I just stopped completely

I have obviously taken up smoking pot, and I have smoked with many first timers, and I can say for myself that my first two times did not get me, but the third time worked. Don't get frustrated if you would still like to smoke pot. Just keep trying and it will hit you like a brick wall.

I saw a few people saying that they don't get high even when straight out eating weed. There's a reason for this the THC (what makes you high) doesn't have any effect unless it is burnt i.e. through smoking or cooking. And the people who smoke it and don't get high, there could be 2 reasons for this, either your dealer is ripping you off and selling you fake weed (which I doubt) or you simply don't know how to inhale. I suggest you guys watch a few tutorials on YouTube on how to inhale properly. No one is genetically immune to weed, you smoke it right you will get high guys. When i first started smoking a long time ago I thought the same as you guys, I thought I was inhaling properly but I wasnt. Practice makes perfect. Peace.

Alright, so I am new to smoking weed. I smoked a bowl with a few friends twice in the past month when I was drunk but that was the only time I have ever done it. Maybe I didn't inhale enough last time and maybe since I was drunk that had something to do with it but I didn't feel it. This time I was determined and my buddy gave me  a pot cookie so I could get high that way. I took the whole cookie (should be plenty for me since I never get high) and nothing happened. He said he is going to give me a free one back and told me to take 2 next time. Why didnt it work? Any Ideas?

Me too...Smoking the best but no effect here in Amsterdam...and plenty of it...into my lungs...

Marijuana had no affect on me the first 8 times or so, but the more u do it & more u hit it, its easier to get high .

Many first timers say they can't feel it.  Keep trying, and one day you will be blown away.

First of all John, its THC

Do you do any other drugs or take any medication? Could be messing with chemicals in the brain. Quite strange you wouldnt feel anything at all, as nature has quite literally engineered us as a species to be sensitive to cannabinoids. 

Can I ask why u smoked for 2 years if it didn't work on u?

That's my exact story! I want to know to!!

I am the same was in amsterdam and had 2 joints (i have not smoked weed in 7 years) and nothing but my hands felt abit weird lol like tingle in them that was just annoying, then when came back to the UK i have had 2 or 3 joints with friends and nothing even had 4 bongs not a thing :/ really weird because a can remember wen i was like 14 and tried it I use to have really really bad trips...