I have been on Zoloft for 5 years I started at 25 and I am currently at 100mg. I smoke at least once a day if not twice and I have never had any issues with smoking, However when I eat it I get massive panic attacks. Like others have said I am not saying it is safe for you, but I have not had any problems.
1. Venlaxafine is the generic of Effexor. It's an SNRI, not an SSRI.
2. Sertraline is the generic of Zoloft. It's an SSRI. Different mechanism, different active ingredient.
3. The Erowid page you linked listed ONE anecdote if negative reaction - with venlaxafine, NOT sertraline - and says next to it that the "experience report" is conflicting.
Make whatever choices are right for you, but don't propagate paranoid misinformation.
the only withdrawal from marajuana is loss of apetite. everything else is in your head buddy
I had been on 50 MG of Sertraline for about half a year when I first started using cannabis. Weed was healing and life transforming as I saw my anxiety shrink to almost non-existent levels. I smoked pretty much every day for a year and never had a bad trip, and the two drugs seemed to work in tandem to improve my life. Then I made the terrible mistake of going cold turkey on the Sertraline. I guess I thought that since cannabis was working so well to ease my anxiety that I could eliminate the pharmaceutical and treat myself, as I saw it, it "naturally". After about 5 days off of the anti-depressant, I smoked some strong weed and had the mother of all bad trips that lasted hours. I felt like my sanity was slipping away at times. I had never before experienced anything like this and it was beyond awful. I have now been back on Sertraline for a couple of days and the dizziness is horrific. My sensitivity to cannabis seems to have quadrupled, as even the smallest amount now causes paranoia, and the calming effects that I'm used to are almost non-existent. At this point, I hope that my chemistry will re-acclimate to the anti-depressant in a few days and all will return to normal, though I fear that that might not happen. Cannabis has been such a beautiful part of my life that giving it up seems like too much to take. I would advise anyone who is using both without issues to NEVER stop taking your dose of Zoloft in order to switch to weed exclusively as a means to treat your anxiety. It f**ks your chemistry. I just hope I can get back to the normal use of both after this stupid mistake.
I've been smoking weed for about 1.5 years with absolutely no problems. 2.5 weeks ago I was put on Zoloft 50mg per day. I smoked for the first two weeks and upped my dose to 100mg at 2 weeks as recommended by my doctor. When I smoked that night, I had a very severe panic attack which I've never had in my life.
First thing that happened was I thought I was hearing voices through the white noise of my fan. This freaked me out and no matter what I did to try and calm myself down, it only got worse. It started with extreme hot flash, tingling in brain, sweating, arrhythmia, dizziness and ADRENALINE.
This led to icing feeling all over my skin, lungs and lips due to hyperventilation. Shortly after, I got tremors in my legs and it was hard to control my muscles. I thought I was dying and even made peace with my life and waited to lose consciousness. It lasted about an hour before I started to come down some what. Another 30 minutes or so of up and downs with those symptoms before I fell asleep.
The next few days I had random adrenaline rushes thinking it was coming back. I dropped by dose back down to 50 mg per day and quit smoking cannabis. I haven't had this since. I don't think it was a panic attack though I do believe I made it worse. There is definitely some kind of interaction with Sertraline and cannabis.