My Jack Russell was diagnosed December 2012, he was in pretty bad shape. We opted to treat naturally because he did not respond well to either of the 2 meds we tried. The first thing I did was change his diet to a low fat diet, this disease will affect the pancreas. I made him chicken, rice and vegetables and once improved I started mixing in an extremely high quality dry food. Very high quality. Keep the fat content low, around 10%, again, this disease will have an impact on the pancreas. While on the homemade diet we also gave Only Natural Pet Ultimate Daily Vitamins, he still gets those even though we have added the high quality kibble. It's important to supplement the homemade diet with some vitamins and nutrients. I also use Cushex drops that I can't say enough good stuff about, they made a huge difference. Right now he is doing fantastic, in fact I had to have blood work done recently for dental work and his blood work came back completely normal. I was told without the meds he would not lose the weight and pot belly that the disease causes. He weighed in at 40 pounds when diagnosed, the whole reason we took him in the first place was the weight, it just couldn't be explained because he ate normal and no more than my female Jack who is completely healthy. It's then they asked about frequent peeing, hair loss, panting, etc and I said yes, we are encountering all of those things, so they kept him overnight and did the test which came back positive for Cushings. 5 years later he now weighs 20 pounds. Right now excessive shedding is the most noticeable thing we are dealing with and I have brought in a little coconut oil to see if we can curb it some. His weight is fantastic, no excessive panting or excessive water intake. He is doing very well, I was shocked when his blood work came back completely normal. When I asked the vet about it she said everything looked good, there was a slight elevation in his liver enzymes but she said it was very slight and nothing at all concerning.