Lupus and RH Negative

I was diagnosed with Lupus last year. I am B neg. My mum has severe psoriasis (she is on cancer drugs to suppress it because it is so severe) and she is also negative.  

I took a chance and googled the association with Lupus and RH negative (A negative, very rare).  I am also RH negative and I have lupus.  I have four children and had to receive a rhogam shot for all four of my pregnancies.  I want to explore this further and find it very interesting.

Quote:

anonymous wrote:

I'm the adoptive mom of two children whose birth mother has lupus -- and is also Rh negative. (Their birth grandmother also had an autoimmune disease, though apparently not lupus and not genetic).

In fact, I think being Rh negative must predispose people to autoimmune diseases; a friend of mine is Rh negative and has polycystic kidney disease, another autoimmune disease.

polycystic kidney disease has nothing to due with ab-rh neg blood and is not a autoimmune disease its a inherited disease in order to have it one of your parents had to have it to give to you.

BUT kidney disease is said to have been related to if not caused in acourance with an auto immune disease.... just sayin....

I am also RH-. Ive delt with health issues my whole life but always found an excuse for all of them, even the things the doctors couldnt figure out. Ive thought of all ive went through in my 5 pregnancies and my 2 miscarriages... my surgeries and my blood transfusion... all the issues that surface with the fact im RH- . I recently have been having auto immune symptoms and have been tested for MS and Lupus, though i have many many signs of lupus, my neurologist isnt sure thats what it is... Im now waiting to get a spinal tape and awaiting referral to a rehumatologist. Ive been researching everything i can find on auto immune diseases and though they have been around as long as we have, doctors still have the same answer to alot of ours questions..... "Im unsure". I started thinking about my blood type and how sick ive always gotten for no reason... Which lead me to the same question that brought us all to this page. I have yet to find any documented research on this issue and wonder if its just that no ones ever questioned it, and if they have, then they must not have pushed the fact. I think that all of you and I should bring this up to ALL of our doctors and to researchers to find an answer to this question. It seems more so then not, that most people with auto immune disease are rh- i found this mostly in alot of lupus patients comments. I do wish you all the very best, and remember, though we dont have a digree in this, it doesnt make us stupid, dont be afraid to question, or challenge any part of your diagnosis and recovery. The only way to get answers is to demand them. :)

ppls still don't get it . tampering with ones immune system via vaccines can be a disaster. i believe these agents could have alot to do with autoimmune problems as they can establish a perminent infection .

I'm A neg and have cystic kidneys. Interesting

I too have lupus and my sister she died from It we both are Rh negative I am Ab. my 2 brothers in other sister are not negative and they have no autoimmune symptoms. my mother and aunt are Rh negative and both have Raynaud's.

My name is Erica and i am O RH negative i was diagnosed with hypothroid about 5yrs ago i have never been tested for Lupus but it now concerns me from what i have read i have an identical twin sister aswell she has the same blood type awell. she was diagnosed with polysystic ovarie syndrome when she was 24yrs old i dont have the same problem

I have elevated ANA - My ENA screen just came back positive for SS-B/La - so with symptoms (lupus-like), we are looking at either Sjogrens or SLE.

My blood type is A- (my father is A+, my mom says she's "O" but doesn't know if she is pos or neg - going with this theory she should be Rh-)

It's quite clear a lot of us RH- have auto immune - but do all RH- end up with autoimmune eventually? Do people with RH+ with parents that are both RH+, whose parents were both RH+ ever get auto immune?

 

I would love to see their (Rh+) weigh in as well - right now only RH- are stumbling across this post.

 

I am O negative and I have an autoimmune disorder of leukocytoclastic vasculitis. This was brought on I believe by the flu vaccine. There is also a high level of autism among RH negatives that is often apparently triggered by vaccines and I am wondering if it is the thimerosol as hypothesized or because vaccines are formulated using blood from other blood types that are not RH negative precipitating an autoimmune response.

well blood type is also inherited so it would follow.

If immunization triggers autoimmune disease in negative RH factors , that would explain both the rise in both autoimmune disorders and autism.

My name Is Erica and i am also O RH negative i am one of an identical twin i have Hypo throid disorder i was diagnosed about 5 years ago i am 38 yrs old soon to be 39 this december my twin sister does have the same blood type as well she was diagnosed with polycystic overie syndrome when she was in her twenties i on the other hand do not have the same problem as her.

Hi Silvia my name is Erica my twin sister and i are both O RH negative i have hypo throid disorder as well it was brought on by some treatment i had about 5yrs ago my mother has auto immune throid disorder aswell very intresting not many people in the world carry our blood type only 7% of the world population has our blood type we have liquid gold as the blood labratories would say lol

Back in late 1982 I had come across a Reader's Digest article (sorry, I don't know the date of publication) about Lupus and the Rh factor.  I don't remember all the details, but the gist of the article made the argument that there was a link between Lupus and a woman having a negative blood type, and that multiple pregnancies of babies with a positive blood type was a major instigator for Lupus.  The only reason this particular article was so noteworthy was because my mother had been diagnosed with Lupus a few years before, and had had several miscarriages, a stillborn child, and 5 children that all survived, some of whom had Rh positive blood.  The article stood out because my mother fit all the criteria.  Unfortunately the publication belonged to someone else, so I did not keep it, and have never been able to find it again since.

I personally am convinced there is a connection between an Rh negative blood type female and Lupus, but I lack the qualifications to support my claim.  I would love to find that article again just to back up this theory.

If there has not been any research aimed at finding a link, there should be one, and soon.

Any studies would be too late to help my mother, she passed away suddenly in 1988 at the young age of 57.  According to the autopsy her death was heart failure due to lupus, despite the fact that she had just received her first chemotherapy treatment for non-Hodgkins type lymphoma an hour or so before she died.